A low glycemic diet may also be important for itching as well as general health. I have noticed that I have more itchy skin when I eat a lot of sugar and refined carbohydrates. The diet that works the best for me to prevent getting itchy consists of cooked foods (cooking helps kill off any fungus or other microbes) that are low on the glycemic index. I think I itch more with the high blood sugar because that is what fungus and related organisms that make you feel itchy may be feeding off of. The best diet for me seems to be mostly cooked meat, nut, vegetables, fruits, and some beans with low glycemic values . For more information you can also read The Paleodiet by Loren Cordain, or visit his web site.
Combined pituitary hormone deficiency (including ACTH deficiency) due to genetic pituitary abnormalities is rare. ACTH and cortisol deficiency have been described in patients with multiple pituitary hormone deficiencies due to mutations in the PROP-1 (Prophet of Pit-1) gene, even though PROP-1 is not expressed in corticotropes. The onset of cortisol deficiency, which may be severe, ranges from childhood to late adulthood [ 2-5 ]. Mutations in other transcription factors involved in early pituitary development (HESX1, LHX4) also can result in variable degrees of hypopituitarism that include ACTH deficiency [ 6,7 ]. (See "Causes of hypopituitarism", section on 'Genetic diseases' .)
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