Y Ishizuki and others. The Effects on the Thyroid Gland of Soybeans Administered Experimentally in Healthy Subjects. Nippon Naibunpi Gakkai Zasshi 1991, 767: 622-629. Feeding 30 grams (2 tablespoons) roasted pickled soybeans per day for three months to healthy adults receiving adequate iodine intake caused thyroid suppression, especially in the elderly. Hypometabolic symptoms (malaise, constipation, sleepiness) and goiters appeared in half the younger subjects (mean age of 29) and half the older subjects (mean age 61). The symptoms disappeared 1 month after the cessation of soybean ingestion. “These findings suggested that excessive soybean ingestion for a certain duration might suppress thyroid function and cause goiters in healthy people, especially elderly subjects.” Note that 30 grams per day was considered “excessive” by these Japanese researchers.
A variety of infectious agents may be transmitted by transfusion. Definitive evidence of transmission by transfusion requires demonstration of seroconversion or new infection in the recipient and isolation of an agent with genomic identity from both the recipient and the implicated donor. Strong presumptive evidence of transfusion transmission includes recipient seroconversion within an appropriate interval after transfusion, the recognition of appropriate infectious markers in an implicated donor on follow-up investigation, or both. Transfusion transmitted disease should be reported to the Australian Red Cross Blood Service.