Regardless of what topical agent you use, steroid or otherwise, “[f]irst and foremost, though, it is essential that the skin barrier [be] protected and maintained with the use of emollients,” meaning moisturizers, “ideally…once or twice” a day, especially right after showering, to lock in the moisture. Petroleum jelly, like Vaseline, is highly effective, but it’s kind of greasy and messy. What about something like coconut oil, which is less greasy? It was found to improve skin dryness, though no better than mineral oil, which is cheaper. Is mineral oil safe, though?
Gynecomastia is a common adverse effect of bicalutamide (Casodex) therapy that may prompt some men to discontinue prostate cancer treatment. Tamoxifen has been recommended as a preventive agent for gynecomastia in these patients. A double-blind study of 282 men randomized to receive 20 mg of tamoxifen once per day with bicalutamide or bicalutamide alone found that after six months, gynecomastia and breast pain were significantly reduced in men who received tamoxifen ( versus percent in the control group). 41 An Italian randomized controlled trial of 80 participants also found that 20 mg of tamoxifen once per week is as effective as 20 mg once per day. 42