In the past several years, some newer medications have come on the market; these are commonly referred to as COX-2 inhibitors . Remember, all NSAIDs work against cyclooxygenase (COX). Traditional NSAIDs (. Ibuprofen, Motrin, Aleve) work against both COX-1 and COX-2. COX-1 and COX-2 are both types of cyclooxygenase enzymes that function in your body. The new medications (. Celebrex) work primarily against COX-2, and allow COX-1 to function normally. Because COX-1 is more important in producing the protective lining in your gut (gastric mucosa), these newer NSAIDs are believed to have less of a risk of causing stomach ulcers.
Hi Norman, You might be interested in the following:
1) Turmeric extract – See more information and studies in my article “ Turmeric Extract is Effective as Ibuprofen for Knee Osteoarthritis “.
2) Gelatin – see more information and research in my article “ Gelatin and Osteoarthritis of the Knees “.
3) Sesame seeds – more information in my article “ How To Use Sesame Seeds For Knee Osteoarthritis “.
4) Tart cherries – see “ How to Fight Joint Pain and Inflammation With Tart Cherries “.
5) Anti-Inflammatory Smoothie for Joint Pain .
6) For pain relief – massaging the area with these 20 essential oils to relieve pain and inflammation , and/or consuming this anti-inflammatory and pain relieving turmeric ginger tea .
7) See more possible natural treatments HERE , and HERE .
The recommendations in this guidance represent the view of NICE, arrived at after careful consideration of the evidence available. When exercising their judgement, health professionals are expected to take this guidance fully into account, alongside the individual needs, preferences and values of their patients. The application of the recommendations in this guidance is at the discretion of health professionals and their individual patients and do not override the responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/or their carer or guardian.