As with anything, to much of a good thing can be bad. Lets look at water, delicious and necessary for all life on earth but too much is called drowning. Any supplement can be bad if way too much is taken, AKA abused. When prohormones are taken as recommended they are safe, or the FDA wouldn’t allow you to buy them at the store or off of this website. Just to make sure, I have ran human trials and found the products by AMS to be safe. I don’t know the exact compounds, because it was a double blind prospective human trial: the highest level of human study.